Volume is key for trading - I'm guessing Cryptsy has more, but I could be wrong.
Depends. I know guys that trade on low volume exchanges and rake in the crypto. They use different strategies for low volume, and it works for them. Higher volume is what most people plan for, so, it's kind of a self-fulfilling prophesy there.
No, you are probably right - "normal" technical analysis and techniques for regular markets such as stocks, futures, or commodities cannot be applied to the
BTC and altcoin markets.
My greatest fear, though, is hodling some huge stash of "whatever" coin, but with no volume, essentially left as the last "baghodler"