What was the result of this?
Bad, ignorant jokes. Episodes where they pull the comedians all from one group (this time, was people involved with a show called "Community") always seem significantly less funny. Middle woman may have known what bitcoins were because she said it was a way of buying drugs without seeing your dealer (host mentioned it was drug money in the prompt, so that may've been why she wrote that).
I think the host (Chris) may've been familiar. The comedians were "making it rain bitcoin" and the host said something like "no, that's what bitcoin actually looks like -- you can't see it."