In my own, in choosing about the four selections I must prefer on Binance exchange. They are both good exchanges especially Bittrex exchange but I think the best exchange among of all is Binance. Easy to use and have a good exchange interface that even newbie can do trading at the first time. Aside from that, it has a large volume in trading that can surely you have a good profit especially in day trading.
I've tried a lot if exchanges and I've never experience any problem. Delays isn't a big problem in any exchanges but it's normal due to heavy traffic on blockchain and also internet connection interference.
But be sure to check the site for security reason and don't let anyone to scam you.