Is it safe to run my GPU fan at 100% speed every time? I noticed that it's throttling due to a high warm rate, can I do this or not? Will my fan die faster than running at 60% speed?.
Of course, the fan will break faster. If your video card is under warranty, then you should change the fans when it breaks.
If you want the cooling system to last longer, then install additional fans to blow air or consider buying a closed case.