As long as you keep playing, the chances of hitting the 1000x in the game will always be there. You may not need to hear this, but to others who will visit this thread and are in the same position as you of never winning or hitting such a high multiplier, you do not need to increase your risk by gambling or staking more. Just maintain your gambling habit, and usually at the time when you least expect, you can be the one we are celebrating.
It might hit or might never hit any win with 1000x.
The risk is with such greed bet target, people will lose in most times of their bets and if they don't manage their finance and gambling capital well enough, they will lose all gambling fund, even get rekt before they can have luckiness to hit 1000x.
Expect to win is normal with gamblers, non gamblers bet without expectation of winning but gambling responsible is something more important for their finance in long term. Chasing 1000x and win with it is very risky if gamblers bet irresponsibly.