There is really no difference, actually major casinos already accept two main crypto currencies so what's the point really? I can go to any major gambling site and deposit with whatever major cryptocurrency I want.
Thats true. Often, established popular casinos are offering major currencies for their players, obviously Bitcoin and ETH are one of these options. As a gambler I prefer casinos offering not only Bitcoin or ETH, having many alts are much better because I can choose the coin I prefer to use that I think is convenient in my part. Usually our concern is about the fees thats why we have different preference what currency to use.
