http://blog.hardcodes.de/articles/43/boost-libraries-on-osx-obstacles-almost-gone
follow along, i'm looking into this too
EDIT:
install_name_tool -change "@executable_path/../Frameworks/libboost_system.dylib" "@loader_path/libboost_system.dylib" DigiCube.app/Contents/Frameworks/libboost_filesystem.dylib