Wall Observer BTC/USD - Bitcoin price movement tracking & discussion

[Biodom]

https://reeserichardson.blog/2024/01/30/the-king-of-curcumin-a-case-study-in-the-consequences-of-large-scale-research-fraud/

"Curcumin doesn’t work well as a therapeutic agent for any disease.

...hundreds of millions of taxpayer dollars, countless hours spent toiling by junior scientists, thousands of laboratory animals sacrificed, thousands of cancer patients enrolled in clinical trials for ineffective treatments, and countless people who have eschewed expensive and invasive but effective cancer treatment in favor of a store-bought spice, encouraged by research steeped in lies."

 Well I suppose it still makes chickpeas palatable.

And what is the point that journo is making?
That they should not have investigated this compound at all? Without those investigations how would they know if it is useful or not?
In addition, personally, I would rather see them waste 100mil on a bunch of negative results studies than on one 'smart' bomb.

That said, the effort investigating this compound probably should have been much more subdued, like a few mil at most.
Negative results is what gives food for better understanding of anything as they are as important as positive results sometimes, but in this case they clearly overspent by a large margin.

  I think the purpose is simply to inform the world of a scam being perpetrated on them essentially led by one individual with a PhD who is publishing fraudulent research.  It's not my NIH pouring your tax dollars on into it so fill your boots.  It's not just about money though, this story had a profound impact on me - I was downright angry after reading it.

I don't like to give this much personal information but in this case, I think it's necessary.  

  My parents are not young.  I'm happy that they're still able to live on their own with limited support from the rest of the family but about 2 years ago, my dad was suddenly having trouble getting up from his chair or out of bed and barely able to walk.  He was diagnosed with severe rheumatoid arthritis by our family doctor who immediately started him on a high dose of prednisone.  The transformation was amazing and immediate and he got his mobility back almost instantly.  Since the markers for arthritis in his blood were off the charts, the family doctor wanted my dad to have a consult with a specialist (here you have to be referred to one) but it takes forever to see them and covid protocols made things worse some doctors, this one in particular, was only doing phone consults.  Meanwhile, our family doctor began the process of slowly ramping the dose of prednisone down to a tiny 2mg per day and everything was good.  Then after an over-the-phone consult, the specialist wanted him off prednisone, first taking him to 1mg per day.  At 1mg per day, he began having some pain again and when he was totally off it, more pain and less mobility.  He was no longer walking around the block each morning so I made him call the specialist - I was fucking livid when she called and told him to begin taking 500mg of curcumin daily because I had already tagged it as a fad and fuck her replacing a drug that works with some unproven spice especially at my dad's age.  It did nothing for him - NOTHING - now fast forward about two weeks when I took his morning coffee over he was sitting at the kitchen table telling me he didn't know if he could drink a coffee because his hands hurt so much he couldn't move his fingers.  I immediately had him call the specialist who, without a consult or any tests, said, "Well it's not related to what I was treating you for so call your GP."  I'm not a violent man but if it were possible to punch someone over the phone...  Now he's back on 5mg predisone as prescribed by our family doctor and doing his daily walk once again.  He was doing well on 2mg so this is a setback.  The specialist wanted to see him again so I took him in expecting she would apologize for brushing him off but no... she wants to take him off prednisone... again.

 Why would a licensed rheumatologist recommend curcumin to treat a known condition?  What would make her think it's a viable treatment for any condition?  Why would she think long term high dose of spice would be better than long term low dose of prednisone for that condition?  If not prednisone, why not a proven, effective, NSAID instead?  Why Biodom???  WHY?  I don't even care how much they spent researching this fraud it's the far-reaching implications of the fraudulent research that's at issue.  When a specialist swaps a known remedy for a fraudulent fuckin' fad, we're all in trouble.  I have the unfortunate advantage of first hand experience.  

 I have to get moving.  I'm on my way to my parents' place with coffee and a printout of the article.  They can read over it while I vacuum the floors.

Your dad just had a bad doctor, but it is somewhat understandable why they wanted him off prednisone, even if they were mistaken (in this case).
Side effects of prednisone (quoting from the article below):
1. Fluid/sodium retention (could mess up the sodium/potassium balance)
2. Muscle weakness
3. osteoporosis (brittle bones)
4. Stomach ulcers
5. delayed wound healing
6. increased risk of diabetes.

https://www.drugs.com/medical-answers/long-you-prednisone-safely-3561220/

However, it is totally unclear why they started him on curcumin (with all that knowledge that it is bogus) instead of ADT (alternate date therapy) with prednisone that is described in the quoted article.
Perhaps, it is simply an ignorant doctor? The article rages about one Dr, who does not come up as a good researcher, and I was just saying that BEFORE testing it is impossible to know what works and what doesn't.

Many many people (including on WO) take various vitamins (myself included), but very often studies come up that this or that vitamin, all by itself, does essentially nothing if taken for long periods of time. Also, some people (like the character played by Seth Rogan in "Knocked up") claim that weed does magic to some diseases, but apart from glaucoma, the evidence is either thin, contradictory or patchy, imho.

[1714628259]

1714628259

[ChartBuddy]

Explanation
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[JimboToronto]

The banks are starving
They have a family too
Gift them your money

Banks have families?
Who? Governments and maybe
The central banks too?

Maybe insurance
And credit card companies?
One big family!

No need to gift them.
They'll try to take it from us
Like they always do.

[JayJuanGee]

ChartBuddy's 24 hour Wall Observation recap
..
All Credit to ChartBuddy

Something within the link seems broken - or is it just me?

[DirtyKeyboard]

ChartBuddy's 24 hour Wall Observation recap
~snip~
All Credit to ChartBuddy

Something within the link seems broken - or is it just me?

Imgur says it has 5 views while yesterday's was 4, so maybe just you?
Or maybe the price is too low? 

[JimboToronto]

Also, some people (like the character played by Seth Rogan in "Knocked up") claim that weed does magic to some diseases, but apart from glaucoma, the evidence is either thin, contradictory or patchy, imho.

There's lots of evidence that cannabinoids are effective in treating numerous conditions, e.g. epilepsy and COPD.

Cannabis extracts play a big role in keeping my COPD under control, under the watchful eye of my respirologist and in addition to the bronchodilators he prescribes me. He was impressed with the improvement that came with my starting fairly large daily doses of cannabis extract (equal parts THC and CBD) buffered with cacao butter and administered rectally. Rectal consumption bypasses the liver so I don't get high.. If I consumed 200mg of that extract orally, I'd be a vegetable. Of course you can treat my experience as anecdotal as I don't know if there have been any double-blind, controlled studies made of this use of cannabis.

The treatment of epilepsy with CBD on the other hand has been well documented.

https://nyulangone.org/news/study-reveals-how-cannabidiol-counters-epileptic-seizures

Unfortunately the entire subject of cannabis treatment of diseases has been clouded by the fact that it gets people high. Some people who are principally motivated by a desire to get high will want to attribute wonder-drug cure-all powers to cannabis while also touting all the wonderful uses of hemp fibers and seeds. Other will react to this zeal with skepticism and discount any real value as mere fanboyism.

It's important to keep an open mind.

[ChartBuddy]

Explanation
Chartbuddy thanks talkimg.com

[AlcoHoDL]

Haiku's block tonight...
Not much intrigue in The Wall.
But it's a Sunday!

Fuck-you status talk.
Hopium for low-coiners.
A tenth of a coin?

First they laughed at us.
Then they declared war on us.
Now they advertise?

Godzilla less one.
So much praise for this movie.
Added to watch queue.

What's this chart I see?
Optimal allocation?
Rat poison tastes sweet...

Iran on a map?
What did anyone expect?
They're right and they're wrong!

When feeling wounded,
It's so soothing to listen,
To Cohen's sweet voice.

#7wodigestsundayhaikus

[xhomerx10]

https://reeserichardson.blog/2024/01/30/the-king-of-curcumin-a-case-study-in-the-consequences-of-large-scale-research-fraud/

"Curcumin doesn’t work well as a therapeutic agent for any disease.

...hundreds of millions of taxpayer dollars, countless hours spent toiling by junior scientists, thousands of laboratory animals sacrificed, thousands of cancer patients enrolled in clinical trials for ineffective treatments, and countless people who have eschewed expensive and invasive but effective cancer treatment in favor of a store-bought spice, encouraged by research steeped in lies."

 Well I suppose it still makes chickpeas palatable.

And what is the point that journo is making?
That they should not have investigated this compound at all? Without those investigations how would they know if it is useful or not?
In addition, personally, I would rather see them waste 100mil on a bunch of negative results studies than on one 'smart' bomb.

That said, the effort investigating this compound probably should have been much more subdued, like a few mil at most.
Negative results is what gives food for better understanding of anything as they are as important as positive results sometimes, but in this case they clearly overspent by a large margin.

  I think the purpose is simply to inform the world of a scam being perpetrated on them essentially led by one individual with a PhD who is publishing fraudulent research.  It's not my NIH pouring your tax dollars on into it so fill your boots.  It's not just about money though, this story had a profound impact on me - I was downright angry after reading it.

I don't like to give this much personal information but in this case, I think it's necessary.  

  My parents are not young.  I'm happy that they're still able to live on their own with limited support from the rest of the family but about 2 years ago, my dad was suddenly having trouble getting up from his chair or out of bed and barely able to walk.  He was diagnosed with severe rheumatoid arthritis by our family doctor who immediately started him on a high dose of prednisone.  The transformation was amazing and immediate and he got his mobility back almost instantly.  Since the markers for arthritis in his blood were off the charts, the family doctor wanted my dad to have a consult with a specialist (here you have to be referred to one) but it takes forever to see them and covid protocols made things worse some doctors, this one in particular, was only doing phone consults.  Meanwhile, our family doctor began the process of slowly ramping the dose of prednisone down to a tiny 2mg per day and everything was good.  Then after an over-the-phone consult, the specialist wanted him off prednisone, first taking him to 1mg per day.  At 1mg per day, he began having some pain again and when he was totally off it, more pain and less mobility.  He was no longer walking around the block each morning so I made him call the specialist - I was fucking livid when she called and told him to begin taking 500mg of curcumin daily because I had already tagged it as a fad and fuck her replacing a drug that works with some unproven spice especially at my dad's age.  It did nothing for him - NOTHING - now fast forward about two weeks when I took his morning coffee over he was sitting at the kitchen table telling me he didn't know if he could drink a coffee because his hands hurt so much he couldn't move his fingers.  I immediately had him call the specialist who, without a consult or any tests, said, "Well it's not related to what I was treating you for so call your GP."  I'm not a violent man but if it were possible to punch someone over the phone...  Now he's back on 5mg predisone as prescribed by our family doctor and doing his daily walk once again.  He was doing well on 2mg so this is a setback.  The specialist wanted to see him again so I took him in expecting she would apologize for brushing him off but no... she wants to take him off prednisone... again.

 Why would a licensed rheumatologist recommend curcumin to treat a known condition?  What would make her think it's a viable treatment for any condition?  Why would she think long term high dose of spice would be better than long term low dose of prednisone for that condition?  If not prednisone, why not a proven, effective, NSAID instead?  Why Biodom???  WHY?  I don't even care how much they spent researching this fraud it's the far-reaching implications of the fraudulent research that's at issue.  When a specialist swaps a known remedy for a fraudulent fuckin' fad, we're all in trouble.  I have the unfortunate advantage of first hand experience.  

 I have to get moving.  I'm on my way to my parents' place with coffee and a printout of the article.  They can read over it while I vacuum the floors.

Your dad just had a bad doctor, but it is somewhat understandable why they wanted him off prednisone, even if they were mistaken (in this case).
Side effects of prednisone (quoting from the article below):
1. Fluid/sodium retention (could mess up the sodium/potassium balance)
2. Muscle weakness
3. osteoporosis (brittle bones)
4. Stomach ulcers
5. delayed wound healing
6. increased risk of diabetes.

https://www.drugs.com/medical-answers/long-you-prednisone-safely-3561220/

However, it is totally unclear why they started him on curcumin (with all that knowledge that it is bogus) instead of ADT (alternate date therapy) with prednisone that is described in the quoted article.
Perhaps, it is simply an ignorant doctor? The article rages about one Dr, who does not come up as a good researcher, and I was just saying that BEFORE testing it is impossible to know what works and what doesn't.

Many many people (including on WO) take various vitamins (myself included), but very often studies come up that this or that vitamin, all by itself, does essentially nothing if taken for long periods of time. Also, some people (like the character played by Seth Rogan in "Knocked up") claim that weed does magic to some diseases, but apart from glaucoma, the evidence is either thin, contradictory or patchy, imho.

 Okay, without getting too specific, he's well into his 80s and he has a long list of medical issues but diabetes is not a concern.  My dad is always reading me the side effects of every medication he takes.  I'll same the same to you - what about the positive effects?  Without the prednisone, he doesn't walk.  If he can't breathe due to asthma, he needs a puff on his inhaler.  The side effects of lack of oxygen, are much worse that any of the negative side effects of the puffer (osteoporosis).  He's on blood thinners too and the side effects make a nasty-looking list but a stroke could be devastating.  He's s a tough old bird and still wants his independence so mobility is key.  While I don't like to think about it, how many years has he got left?   Side-effects be damned.  Those are for young people to think about.

[ChartBuddy]

Explanation
Chartbuddy thanks talkimg.com

[Biodom]

Also, some people (like the character played by Seth Rogan in "Knocked up") claim that weed does magic to some diseases, but apart from glaucoma, the evidence is either thin, contradictory or patchy, imho.

There's lots of evidence that cannabinoids are effective in treating numerous conditions, e.g. epilepsy and COPD.

Cannabis extracts play a big role in keeping my COPD under control, under the watchful eye of my respirologist and in addition to the bronchodilators he prescribes me. He was impressed with the improvement that came with my starting fairly large daily doses of cannabis extract (equal parts THC and CBD) buffered with cacao butter and administered rectally. Rectal consumption bypasses the liver so I don't get high.. If I consumed 200mg of that extract orally, I'd be a vegetable. Of course you can treat my experience as anecdotal as I don't know if there have been any double-blind, controlled studies made of this use of cannabis.

The treatment of epilepsy with CBD on the other hand has been well documented.

https://nyulangone.org/news/study-reveals-how-cannabidiol-counters-epileptic-seizures

Unfortunately the entire subject of cannabis treatment of diseases has been clouded by the fact that it gets people high. Some people who are principally motivated by a desire to get high will want to attribute wonder-drug cure-all powers to cannabis while also touting all the wonderful uses of hemp fibers and seeds. Other will react to this zeal with skepticism and discount any real value as mere fanboyism.

It's important to keep an open mind.

Agreed.

https://reeserichardson.blog/2024/01/30/the-king-of-curcumin-a-case-study-in-the-consequences-of-large-scale-research-fraud/

"Curcumin doesn’t work well as a therapeutic agent for any disease.

...hundreds of millions of taxpayer dollars, countless hours spent toiling by junior scientists, thousands of laboratory animals sacrificed, thousands of cancer patients enrolled in clinical trials for ineffective treatments, and countless people who have eschewed expensive and invasive but effective cancer treatment in favor of a store-bought spice, encouraged by research steeped in lies."

 Well I suppose it still makes chickpeas palatable.

And what is the point that journo is making?
That they should not have investigated this compound at all? Without those investigations how would they know if it is useful or not?
In addition, personally, I would rather see them waste 100mil on a bunch of negative results studies than on one 'smart' bomb.

That said, the effort investigating this compound probably should have been much more subdued, like a few mil at most.
Negative results is what gives food for better understanding of anything as they are as important as positive results sometimes, but in this case they clearly overspent by a large margin.

  I think the purpose is simply to inform the world of a scam being perpetrated on them essentially led by one individual with a PhD who is publishing fraudulent research.  It's not my NIH pouring your tax dollars on into it so fill your boots.  It's not just about money though, this story had a profound impact on me - I was downright angry after reading it.

I don't like to give this much personal information but in this case, I think it's necessary.  

  My parents are not young.  I'm happy that they're still able to live on their own with limited support from the rest of the family but about 2 years ago, my dad was suddenly having trouble getting up from his chair or out of bed and barely able to walk.  He was diagnosed with severe rheumatoid arthritis by our family doctor who immediately started him on a high dose of prednisone.  The transformation was amazing and immediate and he got his mobility back almost instantly.  Since the markers for arthritis in his blood were off the charts, the family doctor wanted my dad to have a consult with a specialist (here you have to be referred to one) but it takes forever to see them and covid protocols made things worse some doctors, this one in particular, was only doing phone consults.  Meanwhile, our family doctor began the process of slowly ramping the dose of prednisone down to a tiny 2mg per day and everything was good.  Then after an over-the-phone consult, the specialist wanted him off prednisone, first taking him to 1mg per day.  At 1mg per day, he began having some pain again and when he was totally off it, more pain and less mobility.  He was no longer walking around the block each morning so I made him call the specialist - I was fucking livid when she called and told him to begin taking 500mg of curcumin daily because I had already tagged it as a fad and fuck her replacing a drug that works with some unproven spice especially at my dad's age.  It did nothing for him - NOTHING - now fast forward about two weeks when I took his morning coffee over he was sitting at the kitchen table telling me he didn't know if he could drink a coffee because his hands hurt so much he couldn't move his fingers.  I immediately had him call the specialist who, without a consult or any tests, said, "Well it's not related to what I was treating you for so call your GP."  I'm not a violent man but if it were possible to punch someone over the phone...  Now he's back on 5mg predisone as prescribed by our family doctor and doing his daily walk once again.  He was doing well on 2mg so this is a setback.  The specialist wanted to see him again so I took him in expecting she would apologize for brushing him off but no... she wants to take him off prednisone... again.

 Why would a licensed rheumatologist recommend curcumin to treat a known condition?  What would make her think it's a viable treatment for any condition?  Why would she think long term high dose of spice would be better than long term low dose of prednisone for that condition?  If not prednisone, why not a proven, effective, NSAID instead?  Why Biodom???  WHY?  I don't even care how much they spent researching this fraud it's the far-reaching implications of the fraudulent research that's at issue.  When a specialist swaps a known remedy for a fraudulent fuckin' fad, we're all in trouble.  I have the unfortunate advantage of first hand experience.  

 I have to get moving.  I'm on my way to my parents' place with coffee and a printout of the article.  They can read over it while I vacuum the floors.

Your dad just had a bad doctor, but it is somewhat understandable why they wanted him off prednisone, even if they were mistaken (in this case).
Side effects of prednisone (quoting from the article below):
1. Fluid/sodium retention (could mess up the sodium/potassium balance)
2. Muscle weakness
3. osteoporosis (brittle bones)
4. Stomach ulcers
5. delayed wound healing
6. increased risk of diabetes.

https://www.drugs.com/medical-answers/long-you-prednisone-safely-3561220/

However, it is totally unclear why they started him on curcumin (with all that knowledge that it is bogus) instead of ADT (alternate date therapy) with prednisone that is described in the quoted article.
Perhaps, it is simply an ignorant doctor? The article rages about one Dr, who does not come up as a good researcher, and I was just saying that BEFORE testing it is impossible to know what works and what doesn't.

Many many people (including on WO) take various vitamins (myself included), but very often studies come up that this or that vitamin, all by itself, does essentially nothing if taken for long periods of time. Also, some people (like the character played by Seth Rogan in "Knocked up") claim that weed does magic to some diseases, but apart from glaucoma, the evidence is either thin, contradictory or patchy, imho.

 Okay, without getting too specific, he's well into his 80s and he has a long list of medical issues but diabetes is not a concern.  My dad is always reading me the side effects of every medication he takes.  I'll same the same to you - what about the positive effects?  Without the prednisone, he doesn't walk.  If he can't breathe due to asthma, he needs a puff on his inhaler.  The side effects of lack of oxygen, are much worse that any of the negative side effects of the puffer (osteoporosis).  He's on blood thinners too and the side effects make a nasty-looking list but a stroke could be devastating.  He's s a tough old bird and still wants his independence so mobility is key.  While I don't like to think about it, how many years has he got left?   Side-effects be damned.  Those are for young people to think about.

Of course, it's all in balance. When the person is in their 80-ies or 90ies, comfort, mobility and being in a good mood/enjoying life are the most important considerations.
Sometimes a person in his eighties could suddenly turn worse...I have seen it happen...without going into too many details.
Btw, women, on average, live 7 years longer. Nobody knows why, exactly, apart from possible testosterone effects.

[shahzadafzal]

A mandatory meme update:

[Amphenomenon]

Some banks think that we are literally idiots:

Example: Wells Fargo sent out invites to join their premier checking account (an equivalent of a spending account).
Requirement: $250K in deposit and your bonus is $2500 and you have to keep $250K there for at least 90 days.
However, the interest on 250K is about $3312.5 in a money market fund in 90 days.
Question: why would I voluntarily gift WF $812.5 (and more if I keep the money there for longer than 90 days)?
In exchange for what? Well wishes?

shuddup and take my money!!

oh wait

ok, so i guess ill just keep my stack in cold storage and wait for math and greed to do its thing

Seriously, the banks will continue to reap ignorant investors and this another scheme but the government will always support them Afterall government and banks are one while giving citizens irrelevant reasons to not invest in bitcoin.

Actually I was thinking about if it was possible for there to be a choice for employees pension to be invested in bitcoin rather than being kept with the banks because they are literally reaping them off while some banks gives a reasonable in comparison to the others but just imagine someone who was literally having his/her pension on bitcoin for the past 6 years, by now they will know that they are really going to retire well

Spelling failed successfully.

I should have listened to my English teacher sigh

[ChartBuddy]

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[ChartBuddy]

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[ChartBuddy]

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[ChartBuddy]

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[ChartBuddy]

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[ChartBuddy]

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[ChartBuddy]

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