If my assessment is correct, it's in PSV's best interest not to win against Twente. By allowing Twente to earn at least 1 point, it would be guaranteed that Ajax will not get to the 3rd place and will not participate in the Champions League qualifiers in the next season. So it's a chance for PSV to cripple Ajax a little bit financially, as Ajax are their biggest league rivals. I'm not sure of that's the route PSV would take, or will they go for a fair-play approach and play for the win. But even if PSV don't go easy on Twente, Twente themselves are capable of earning points against PSV.
You're too bold to make such an assessment, I don't think they will do that because they will be playing at home. What I see in the bookies is that PSV is still the favorite, I believe the only reason the bookies make them the favorite even though they have already won the league is because of the home match. They don't want to & won't disappoint their fans & supporters with a bad result. But, good luck with your choice, mate.