so if Simon stays abroad and decides to stay abroad, is he out of US jurisdiction?

indeed
http://www.nxtcommunity.org/nxt/nxt/nxt-network-energy-and-cost-efficiency-analysis

"Unlike Bitcoin which is mined, Nxt is forged. Bitcoin mining basically means that computers have to run continually while exerting as much power as they can in order to try to be the first computer to guess a random number approximately every 10 minutes. By exerting this power, they prove that they are real machines and that a lot of money has been spent on these machines in order to secure the network. Nxt has a different approach which is that every minute someone new is chosen to protect the network. The more Nxt you own, the more often you are chosen to protect the network. There are more complexities than this to help protect the network but this is the basic idea. What this means is that only one or possibly a few computers at a time are processing transactions and not wasting energy just for the sake of proving they exist."

http://en.wikipedia.org/wiki/Fred_Hampton
http://en.wikipedia.org/wiki/COINTELPRO

Indeed. things have... gotten more elaborate since the 70s

Speaking objectively, it is because the distribution is low and concentrated in MSC. Like with Bitcoin, the majority of those interested already invested what they were willing to invest in the past, and since  bid support is currently low since it depends on growth and not much has happened in the past couple months, any increasing ask support will send it down like it has been. 'No news is good news', so they say, which I'll admit is not very encouraging.

However, as I understand it, MasterCore as a reference platform will help accelerate development into the other features and there still is $1.8M (3x more than what we first crowdfunded with) to leverage and grow with instead of just simply working under the paradigm of cutting costs. We're reoptimizing effort vs expected output wherever we can with an emphasis of expanding into the most conducive areas of value.

I do not believe so? From what I learned the past few days, MasterCore and Omni********* use mastercoin-tools as a reference, so I believe Masterchain and MasterChest have to update their use of mastercoin-tools when mastercoin-tools gets updated.

Take this as a simple forum reply/musing until someone qualified can reclarify and/or correct me.

but still! Poloniex decided to implement the soon-to-be deprecated mastercoin-tools despite MasterCore alpha being live and beta soon in August. I'm really impressed on their part

well after serving you gain some perspective on what the military's role is in America: defense of commercial interests
I'd donate a few dollars to stop this if Ron Paul can. Others believe Obama will tone down military use

doubtful

I think you can tell from the market price though

It is the Golden Age of Neuroscience. The field is learning new things every day.

http://www.ncbi.nlm.nih.gov/pubmed/15228154
Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition.

MDMA metabolism is rather complex and includes 2 main metabolic pathways: (1) O-demethylenation followed by catechol-O-methyltransferase (COMT)-catalyzed methylation and/or glucuronide/sulfate conjugation; and (2) N-dealkylation, deamination, and oxidation to the corresponding benzoic acid derivatives conjugated with glycine. The fact that the polymorphic enzyme CYP2D6 partially regulates the O-demethylenation pathway prompted some expectations that subjects displaying the poor metabolizer phenotype may be at higher risk of acute toxicity episodes. In this metabolic pathway a mechanism-based inhibition of the enzyme operates because the formation of an enzyme-metabolite complex that renders all subjects, independently of genotype, phenotypically poor metabolizers after the administration of 2 consecutive doses. Therefore, the impact of CYP2D6 pharmacogenetics on acute toxicity is limited. One of the interesting features of MDMA metabolism is its potential involvement in the development of mid- to long-term neurotoxic effects as a result of progressive neurodegeneration of the serotonergic neurotransmission system.

I think there's a George Carlin quote for this

my favorite one was this one

Don't condescend me please. If you any sense of reading comprehension, I refer to molecules that are only synthesized in labs and not synthesized in nature. The example I used, D-ascorbate, is not synthesized in nature. I understand that we can mimic natural chemical processes to synthesize the L- enantiomer configuration of Vitamin C and other naturally synthesized chemicals, but we don't always do this.

And yes, neuroreceptors, but that refers to drugs' mechanism of action upon receptors. I was talking about the byproducts of breaking down synthetic unnatural drugs and the chemical effects from said reactions and the oxidative stress they can induce. I understand that metabolism of natural foods cause oxidative stress too, but the interactions of molecules the body didn't evolve to interact with under optimal living conditions are arguably harder on the body, as resilient as the body is.

Destabilization of neural pathways can be inherent in any addictive drug, synthetic or not. For those not familiar, uppers like caffeine, MDMA, cocaine, and amphetamines increase the release of the amine transmitters of serotonin and dopamine (and norepinephrine, but that is not so much a learning neurotransmitter). Our brains have an equilibrium that uses these neurotransmitters for signaling pathways. When uppers are introduced to a delicate equilibriated system, the novel experience, the resulting flood of serotonin and dopamine, disturbs the brain's learned sense of baseline. Afterwards, under normal conditions (without the drug), the brain would never release the same amount of neurotransmitters without these agonists acting upon the receptors to heavily induce signal cascades of said neurotransmitters.  As such, people feel different, or "off" in some sort, after the comedown of drugs . That's why you see people grow to believe they cannot function as well without caffeine or amphetamines (in addition to the reward learning mechanism that comes from dopamine release). That's why people that go to bad concerts chase that good roll but never are able to again without taking higher doses (excitotoxicity, over excitation of receptors and their subsequent destruction also plays a, probably compounding, role). That's why people don't enjoy parties as much without cocaine if they've had a blast doing cocaine before. I've seen it all before, I'm in a frat. It is reversible.

it's the same thing with opiate abuse. Our body has a learned sense of equilibrium of pain. We sit here and we're healthy and nothing is causing us pain, it is because opiate system is in equilibrium. When you flood your opiate receptors with heroin, your brain feels a rush of pleasure and your learned baseline ticks up a bit towards a higher level of opiates for what it considers should be normal. When the opiate leaves the system, since the baseline is adjusted, people feel a bit off because their bodies do not naturally release as many opioid neurotransmitters as compared to when induced by an opiate. If a cycle of abuse is established, the baseline ticks up higher and higher. In the event an addict cannot get more, the pain baseline is so high that without an external agent inducing more opiate release, the normal trickle of opioid neurotransmitters from the brain will not enough for normalcy and addicts actually start feeling pain. Again, reversible, but not easy.

Anyway, what I was trying to say with synthetic psychoactive drugs is that they attempt to specifically target these receptors and as such destabilize the equilibrium and in addition to their possibly unnatural synthesis, the resulting decomposition might have adverse effects on the body as well, perhaps moreso than naturally synthesized analogs.

Not exactly. I'm claiming that synthetic molecules that would not exist from organically (perhaps co-)evolved processes (i.e. not in a lab from fallible humans playing God) tend to not be meant for our bodies which evolved in for the most part untampered nature for the majority of our timeline. As an example, synthetic Vitamin C (D-ascorbate) is not the full Vitamin C complex (L configuration of ascorbate):
"Ascorbate may also act as an antioxidant against oxidative stress. However, the fact that the enantiomer D-ascorbate (not found in nature) has identical antioxidant activity to L-ascorbate, yet far less vitamin activity,[3] underscores the fact that most of the function of L-ascorbate as a vitamin relies not on its antioxidant properties, but upon enzymic reactions that are stereospecific.

[3]Aboul-Enein HY, Al-Duraibi IA, Stefan RI, Radoi C, Avramescu A (1999). "Analysis of L- and D-ascorbic acid in fruits and fruit drinks by HPLC". Seminars in Food Analysis 4 (1): 31–37.

So, my supposition is that things like MDMA and amphetamines are typically bad for you because 1) the chemical reaction from breaking these molecules down is not something our bodies evolved to break down and 2) the bioactivity from these reactions taking place in our bodies disturb the sensitive equilibrium they were meant to operate at.

I'm of the opinion that most synthetic/unnatural drugs end up destabilizing the equilibrium under which neural feedback pathways work. Because Ricaurte's studies were so high-profile and foundational, it is only natural that subsequent papers on MDMA tend to cite them. Psychology papers advocating their therapeutic use probably won't cite Ricaurte. I do not care to challenge your devil's advocation of others biases as prudent as it may be because I've many a friend that are in this scene so I've observed quite a bit first-hand, as well as being a student of neuroscience with my own predilections from my own learning.

MDMA is no good and due to the settings and culture it's typically abused in, especially harmful. In the same way to me that amphetamines are no good, but to a much greater extent.

 

I said this a few posts back but I don't quite recall the number either.

http://www.emcdda.europa.eu/themes/harm-reduction/consumption-rooms

 I still don't personally approve but to each their own