You can lose profit sending trading and withdrawing if you are trading a small amount I have $50 worth of Ferum or FRM it will take $6 to send the whole amount to Bilaxy and after you trade it to Eth and wants to withdraw it you will have to spend $12 to withdraw your Eth,
now that's $18 gas fees for your $50, my only option is to trade it to other altcoins like DGB or Litecoin which offer $4 to $5 fee you still going to lose $11, that's over 20%.
Yes you can lose funds while trying to send out and withdraw; but also you can be smart about it; and to be smart about it you need to be friends with ethgasstations, and check up gwei prices until you have a cheap gwei and cheap gas fee to send out your token (you can still send out with 2$ in this bull run, if you are patient). Also, while withdrawing your funds from an exchange platform, normalize focusing on xlm, or the tron blockchain; with trc20 usdt or tron token; you can withdraw from exchanges for as low as 1$. Always do your research.