i think the best trick is to unlock wine as soon as possible, and sell it alongside with beer.
when you can, unlock whisky as soon as possible, and sell all 3 drinks , rotate them...
then upgrade your buildings , step by step everything, your eceonomy will give you more and more satoshis..
then start to make science, it will almost double your income...
then work on inventions, that is new thing in virtualpub..
i am not recommending to withdraw so much until you havent all unlocks made...
i am suggesting to turn on popunders and claim event every 30 mins... (1 popunder / hour will not kill you)
also check the bottom of the page for 4 hour bonuses, it gives you extra satoshis...
there is also small faucet with 30+ satoshis daily
if something is unclear, i am here almost non stop for the players